Endocrine Abstracts

Determination of radiochemical purity (RCP) of radiopharmaceuticals based on 68Ga-BCA-peptides (68Ga-DOTA-TOC/-TATE, 68Ga-NODAGA-RGD2, 68Ga-PSMA-HBED-CC, etc.) is an extremely important part of QC in routine clinical practice. Nature of gallium leads to formation of two major radiochemical impurities in the radiopharmaceutical: hydrolyzed 68Ga (colloid) and unbounded ionic forms of 68Ga. The amounts o...